Applying a patch to esxi 5 without reboot or booting from cd

src: http://www.arkf.net/blog/?p=307 

For ESXi 5, instead of using esxupdate ( I guess esxupdate is deprecated ), use esxcli :

esxcli software vib install -d /vmfs/volumes/4be1f209-78ae1314-33c5-001b213d3c53/patches/ESXi500-2012813.zip

src: http://www.arkf.net/blog/?p=307